https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Mepolizumab and Oral Corticosteroid Stewardship: Data from the Australian Mepolizumab Registry https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47085 Tue 13 Dec 2022 16:35:23 AEDT ]]> Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39063 Tue 03 May 2022 11:38:18 AEST ]]> Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54560 Thu 29 Feb 2024 10:27:50 AEDT ]]> Managing patients with severe asthma in Australia: current challenges with the existing models of care https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34913 Thu 27 Jan 2022 15:59:20 AEDT ]]> Oral corticosteroids stewardship for asthma in adults and adolescents: A position paper from the Thoracic Society of Australia and New Zealand https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49460 1000 mg prednisolone-equivalent cumulatively are likely to have serious side effects and adverse outcomes. Patient perspectives emphasize the detrimental impacts of OCS-related side effects such as weight gain, insomnia, mood disturbances and skin changes. Improvements in asthma control and prevention of exacerbations can be achieved by improved inhaler technique, adherence to therapy, asthma education, smoking cessation, multidisciplinary review, optimized medications and other strategies. Recently, add-on therapies including novel biological agents and macrolide antibiotics have demonstrated reductions in OCS requirements. Harm reduction may also be achieved through identification and mitigation of predictable adverse effects. OCS stewardship should entail greater awareness of appropriate indications for OCS prescription, risk–benefits of OCS medications, side effects, effective add-on therapies and multidisciplinary review. If implemented, OCS stewardship can ensure that clinicians and patients with asthma are aware that OCS should not be used lightly, while providing reassurance that asthma can be controlled in most people without frequent use of OCS.]]> Thu 18 May 2023 12:40:23 AEST ]]> Mepolizumab effectiveness and identification of super-responders in severe asthma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40118 Fri 22 Jul 2022 13:48:23 AEST ]]> Treatable traits can be identified in a severe asthma registry and predict future exacerbations https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37892 Fri 01 Apr 2022 09:25:28 AEDT ]]>